The SCN2B Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SCN2B. This antibody recognizes Human antigen. The SCN2B Antibody has been validated for the following applications: Western Blot.
Description
Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier By similarity.Eubanks J., NeuroReport 8:2775-2779(1997).Bolino A., Eur. J. Hum. Genet. 6:629-634(1998).Cruz J.S., Science 284:711-711(1999)